|Calhoun County South Carolina Cities/Towns - Cameron, Creston, Fort Motte, Lone Star, Saint Matthews (County Seat)
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Calhoun County is a county located in the U.S. state of South Carolina. A 2016 Census Bureau estimate placed the population at 14,796. Its county seat is St. Matthews.
It is named for John C. Calhoun, the former U.S. Vice-President, Senator, Representative and cabinet member from South Carolina. It was formed in 1908 from portions of Lexington and Orangeburg counties.